Midrimax eye drops: instructions for use, analogues, reviews
It is not a secret for anyone that for many ophthalmologic procedures, including some operations, it is important that the pupil of the patient be maximally enlarged. Of course, to achieve such a state in a natural way is impossible. In such cases, use special drugs. And often ophthalmologists use Midrimax eye drops. Instructions for use suggests that the drug really dilates the pupil.
Of course, many people want to get as much information as possible about the medicine used. What is included in the composition and how does the Midrimax drop affect the body? Instructions, contraindications, the likelihood of adverse reactions, price and reviews - these are the moments that draw attention to many people.
Information on the form of release and composition
This drug is available in the form of eye drops.It is a colorless liquid, placed in vials with special convenient dispensers for instillation. The volume of the bottle is 5 ml. What is included in the drug "Midrimaks"? The instruction says that the medicine contains two active ingredients, namely, phenylephrine hydrochloride (50 mg per 1 ml of solution) and tropicamide (8 mg in one ml of the preparation). Naturally, some auxiliary agents are present, namely, purified water, edetate disodium, sodium metabisulfite, as well as sodium hydroxide, hypromellose, benzalkonium chloride and a small amount of hydrochloric acid.
The main properties of the drug
The main components of the drug cause persistent dilation of the pupil, as well as accommodation spasm. Such an effect is useful when conducting various ophthalmic procedures. The drug blocks the cholinergic receptors, which are located on the ciliary muscle and the iris sphincter.
As evidenced by reviews and research results, the effect of eye drops appears quickly. The pupil expands 10-15 minutes after applying the drops. The same applies to temporary accommodation paralysis.The maximum effect lasts about 35-40 minutes, which is enough for a medical procedure. Paralysis of muscles passes after 1-2 hours. Full restoration of the size and function of the pupil is observed approximately 6–7 hours after instillation.
The active ingredients quite easily and quickly penetrate the tissues of the eyes, and then enter the general bloodstream. It is worth considering that the drug has some systemic effects. Active substances and their metabolites are excreted by the kidneys along with urine.
When does a doctor prescribe eye drops?
When is it appropriate to receive drops for Midrimax eyes? The instructions for use contain information that in modern ophthalmology the drug is used in two cases:
- Diagnostic ophthalmologic procedures that require pupil dilation.
- Surgical procedures and laser surgery.
Of course, the attending physician will independently determine whether these drops are exactly what you need. Moreover, their use is possible only in the hospital where the patient is under the supervision of a physician.
The drug "Midrimaks" (eye drops): instructions for use
In no case is not allowed independent use of this drug. Only a doctor can prescribe and introduce drops for the eyes "Midrimaks." The instructions for use contain only some general recommendations. The procedure is carried out 15-30 minutes before therapeutic or diagnostic measures. The doctor gently digs 1-2 drops into the conjunctival sac. After a few minutes there is an expansion of the pupil. This is the way that Midrimax eye drops are used. Instructions for use for children looks the same.
Since the active components of the drug penetrate into the systemic circulation, they are not allowed for all patients. The list of contraindications should be found before using the medication:
- Of course, drops can not be taken if the patient has an increased allergic sensitivity to any of the components.
- Contraindications include vascular and heart diseases, in particular, atherosclerosis of the coronary arteries, angina, arrhythmia and hypertensive crisis (or the risk of its development).
- Drops are not used for glaucoma of the angle-closure or angle type.
- The drug should not be prescribed to patients who take monoamine oxidase inhibitors (the use of drops is possible no earlier than three weeks after the end of therapy).
- The drug has an age limit. It is not recommended for patients under 18 years of age, although in this case the decision is made by the doctor, because the drops are sometimes used in pediatric ophthalmology.
- Contraindications include some endocrine diseases, including thyrotoxicosis and diabetes mellitus of the first type (in diabetes of the second type, the use of drops is possible, but this should be done very carefully).
- The drug should not be prescribed to pregnant women and mothers during breastfeeding.
Local adverse reactions during therapy
Statistics and doctors suggest that the drug rarely causes side effects. On the other hand, their appearance is still possible, and from time to time complications are recorded. Some patients complain of allergic reactions, which are accompanied by redness, burning in the eyes and itching. Sometimes the use of drops is accompanied by a decrease in vision and soreness, but these effects, as a rule,pass by themselves. In some people, lacrimation and pigment release are observed after the injection. Local side effects include swelling and hyperemia of the conjunctival membrane. The development of reactive miosis is also possible.
Is it possible the emergence of systemic disorders during therapy?
As already mentioned, the active components of the drug penetrate into the systemic circulation, therefore complications are possible not only from the side of the eye - sometimes the drug negatively affects other organs. Some patients develop common allergic reactions, which are accompanied by redness and itching of the skin, the development of contact dermatitis. Some patients complain of dry mouth. Sometimes after applying the drops, you can notice a strong redness or, conversely, pallor of the skin.
There is a possibility of a complication of the cardiovascular system. In particular, tachycardia or bradycardia may appear in patients. Sometimes there is an increase in blood pressure. Occasionally, patients develop coronary occlusion. The most dangerous complications are myocardial infarction and embolism.(blockage) of the pulmonary artery. These are serious conditions in which emergency medical care is needed.
The list of possible systemic reactions include dizziness, headaches, which are accompanied by vomiting, as well as some other disorders of the central nervous system. Some people had muscle rigidity. Perhaps a decrease in the tone of the muscles of the digestive tract, leading to disorders of peristalsis.
Is it possible to overdose with the drug "Midrimaks" (eye drops)? The instruction contains information that, if used correctly, the drug cannot cause a similar condition, because it is used by a doctor, and long-term therapy is not required. On the other hand, accidental ingestion of the solution is dangerous.
Oral drops may cause hyperthermia and tachycardia in a patient. There is mydriasis and breathing problems. Human skin and mucous membranes become dry. If a large amount of the solution gets into the digestive system, convulsions and even coma are possible. Therefore, the patient should be urgently taken to the hospital ward, where doctors will wash the stomach. Be sure to use sorbents.Further symptomatic treatment, for example, in case of hyperthermia, the patient is prescribed cold compresses, etc.
Interaction with other drugs
What should be known to patients who are prescribed the drug "Midrimaks" (drops)? Instructions for use states that this tool can not be used while taking adrenergic blockers, as it is possible the development of hypertensive crisis due to vasoconstriction. The use of drops during therapy with anticholinergics and tricyclic antidepressants may lead to the same result. If local anesthetics are used with the drops during the procedure, then systemic adsorption of the active components of the medication may be enhanced.
Cost and list of effective analogues
In modern ophthalmology, Midrimax drops are widely used. Instructions for use, properties and composition - not the only thing that interests the patients. For many people, the cost of a medicine prescribed by a doctor is also important. "Midrimaks" - a drug from the Indian manufacturer. Therefore, the cost of funds varies depending on many factors, including the mark-ups of the pharmacy and distributor.The price of the bottle (5 ml) varies from 460 to 600 rubles, which is not so much.
What to do if the given eye drops do not suit you? The reasons for this can be many. In such cases, the treating ophthalmologist will try to find the most effective and safe analog. For example, Tropicamide drops, which contain the same active component, have the same properties. For diagnostic procedures are often used tools such as Appamid and Cyclomed. In any case, you can not select a substitute yourself.
The drug "Midrimaks": instructions for use, reviews of doctors and patients
Of course, the opinion of experts is important. As already mentioned, in some situations it is recommended to use exactly the drops “Midrimax” instructions for use. Analogs, of course, exist, but as far as possible, ophthalmologists use this drug in the procedures. It gives a fairly lasting effect, and there are not so many contraindications for use. Of course, there is a whole list of possible adverse reactions, but they occur extremely rarely. For patients, the cost is not a pleasant bonus.By the way, the drug is easy to get, since many pharmacies are involved in its distribution.